Portable, Convenient, Safer,

What is SmartDialysis?

SmartDialysis is a startup company based in Rochester, New York, USA, with members whose backgrounds vary from biomedical engineering, nephrology, mechanical engineering, business management, and computer science. Our team has been working closely with our partners in the hemodialysis industry.

Our mission is to improve the quality of life and to extend the lifespan of End Stage Renal Disease (ESRD) patients with several generations of portable hemodialysis products. Our ultimate goal is to create a portable hemodialysis device so that ESRD patients wont need to frequent dialysis centers and can enjoy more mobile lifestyles. Our product will allow patients to perform hemodialysis at their own convenience with fewer medical complications and an overall better outcome.

Our Vision

We will gradually introduce to the market a portable dialysis device in three generations.

Product Evolution

Generation I

Old dialysis, new experience.

Our first generation of products will be cartridges that are integrable to current dialyzers. We will include the advanced nano-membranes along with anti-inflammation and anti-coagulation solutions inside the small cartridges.

With the improved medical care, patients can expect a smoother, healthier outcome with fewer complications.

Generation II

Smaller yet better!

Designed to be safe and convenient for both the ESRD patients and the doctors. Our second generation products reduce the extracorporeal blood volume needed and create a safer, smoother dialysis experience.

The products will be stand-alone devices in dialysis centers, and potentially suitable for direct home hemodialysis. Patients using our device will have a better results with fewer complications.

Generation III

No hassle, only buckle.

As a natural flow of our product evolution, our generation II product will feature an attachable, fully portable device, which will save the patients the hassle of travelling back and forth to the dialysis centers.

Centered on the health and convenience of ESRD patients, our design will truly revolutionize the way dialysis process is done. And with it, those who use it will feel the difference. We believe that every ESRD patient deserves to live a normal life without being constrained within dialysis centers. So simple, yet so helpful.

Our Technology

Closely working with University of Rochester and our industrial partners, SmartDialysis is working towards a smoother dialysis process, as gentle as the real kidney, with much less inflammation and much less coagulation. The McGrath research lab at University of Rochester has been advancing the technology of nano-membranes for years. We are also trying to integrating the efficient nano-membranes developed at McGrath research lab to portable dialysis devices.

Our technology will reduce the blood flow rate needed to perform dialysis, thus reducing the amount of vascular access problems. It also creates less inflammation by activating fewer blood cells than current dialysis techniques, and it is able to remove some mid-sized toxic molecules much more quickly.

The use of microfluidics and microelectronics allows our product to become portable and also allows for remote monitoring. This advancement not only has the potential to decrease costs through reducing dialysis center facility and technician costs, but also has the potential to become a practical home hemodialysis system that enables longer dialysis time, such as overnight dialysis, which is generally associated with better dialysis outcomes.

Meet the Team

Aizhong Zhang

Aizhong Zhang is a master student in Technical Entrepreneurship and Management and a PhD candidate in the Institute of Optics, at University of Rochester.

George Anstadt

George Anstadt is an entrepreneurial and broadly experienced physician executive and practicing clinician who currently advises the Serometrix in silico drug discovery company’s Alzheimer project. He recently completed 10 years service as Medical Director of the Humana Clinic in Rochester, NY.

David Wu

David Wu is a Chemical Engineering professor at University of Rochester. His research areas are mainly: 1) Systems biology approach toward biofuels and 2) Bone marrow and lymph node tissue engineering.

Li Deng

Li Deng is a masters student in Technical Entrepreneurship and Management at the University of Rochester. He previously studied at the Michigan State University, where he earned his bachelors degree in Biochemistry and Molecular Biology.

Bowei Zhang

Bowei is a Masters student in Technical Entrepeneurship and Management at the University of Rochester. Previously, he studied Material Science and Engineering at Beihang University in Beijing, China.

David Manly

David Manly is a student in Optical Engineering at University of Rochester. And he is our industrial relation coordinator.

Our Partners

The University of Rochester is home to professor James McGrath, the leading innovator behind the nano-membrane technology. In addition, most of the SmartDialysis team have also earned their degrees from the University of Rochester.

Over the years, around five million has been invested into Dr. McGrath's research lab.


Jim McGrath is the leading innovator behind the nano-membrane technology. He is currently a professor in Biomedical Engineering at the University of Rochester.

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